Space maintainers and regainers are vital in interceptive orthodontics, used to preserve space between teeth, particularly after extractions, and to facilitate the eruption of permanent teeth. These appliances vary based on the child’s dental development stage, the dental arch involved, and the specific teeth missing. They can be removable, fixed, semi-fixed, functional, nonfunctional, active, passive, or a combination of these. Common types include the Nance holding arch, lingual arch, band and loop space maintainer, space regainer, and distal shoe space maintainer. They can be customized to suit individual clinical scenarios, ensuring effective space management and preventing or reducing the development of malocclusions.